“Trumpkins” beware, nevertrumper John Podhoretz has developed a fever for an Oprah Winfrey Presidency. Be careful if you ever get near him, it looks like it might be contagious:

Democrats have the perfect weapon to take down Donald Trump in 2020, according to a conservative columnist: Oprah.

The famed black media proprietor and TV host was thrown into the political mix on Thursday when an op-ed in the New York Post suggested she is ‘uniquely positioned, should she wish to commit herself, to seek the Democratic nomination for president and challenge Trump in 2020.’

John Podhoretz, a never-Trump advocate and former speechwriter for Presidents Ronald Reagan and George H.W. Bush, shared his essay on Twitter – and Oprah answered.

‘Thanks for your VOTE of confidence!’ she wrote back in a tweet.

Podhoretz replied: ‘Give it a shot, what, would it kill you?’

Winfrey starred Sunday in a ’60 Minutes’ segment that had her conducting a focus group of Michigan voters, assessing the range of their political opinions.

Asked about impressions of Trump, their answers ranged from ‘every day I love him more and more’ to ‘he’s a horrible president.

Oprah listened, reflected their answers, and tried not to judge.

Podhoretz wrote that she is the Trump’s ‘mirror image.’

‘Of course, she’s female and he’s male; she’s America’s generous aunt and he’s America’s crazy uncle.

‘And yes, she’s black and he’s white, she’s liberal and he’s whatever he is.’

The columnist later chuckled on Twitter that ‘Trumpkins’ – his derisive nickname for the president’s fans, have been ’emailing me to say my idea Oprah would be strong in ’20 is crazy because she has no experience.’